Kidney Failure & Renal Care

Nephrology

Nephrology is a part of medical science that deals with function and diseases of the kidneys and it aims on the diagnosis and treatment of kidney diseases. The kidneys are paired retroperitoneal organs that lie at the level of the T12 to L3 vertebral bodies. The kidney has a fibrous capsule, which is bordered by pararenal fat. The kidney is divided into renal parenchyma, consisting of renal cortex and medulla, and the renal sinus containing renal pelvis, calyces, renal vessels, nerves, lymphatics and perirenal fat. The renal parenchyma has two layers: cortex and medulla. The renal cortex stays slightly below the capsule while the renal medulla consists of 10-14 renal pyramids, which are separated from each other by an extension of renal cortex called renal columns. The kidneys serve essential functions, including filtration and excretion of metabolic waste products (urea and ammonium); regulation of necessary electrolytes, fluid, and acid-base balance; and stimulation of red blood cell production. They also serve to regulate blood pressure via the renin-angiotensin-aldosterone system, controlling reabsorption of water and maintaining intravascular capacity.